Chloroform → 2-(1-Benzothien-2-yl)-4-chloropyrido[2,3-d]pyrimidine

Reaction equation

[CH:30]([Cl:31])([Cl:32])[Cl:33].[O:25]=[CH:26][N:27]([CH3:28])[CH3:29].[S:21]([Cl:22])([Cl:23])=[O:24].[s:1]1[c:2](-[c:10]2[n:11][c:12]([OH:20])[c:13]3[c:14]([n:15]2)[n:16][cH:17][cH:18][cH:19]3)[cH:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2>>[s:1]1[c:2](-[c:10]2[n:11][c:12]([Cl:23])[c:13]3[c:14]([n:15]2)[n:16][cH:17][cH:18][cH:19]3)[cH:3][c:4]2[c:5]1[cH:6][cH:7][cH:8][cH:9]2

Participants

Reactant 4

HCID 6212Chloroform

HCID 6228Dimethylformamide

HCID 24386Thionyl Chloride

HCID 178517407HCID 178517407, compound

Product 1

HCID 591303752-(1-Benzothien-2-yl)-4-chloropyrido[2,3-d]pyrimidine

Sources & evidence

ORD record: ord-b269e102d65248009e27772af0eeb2fc
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…