Potassium Cation → 6-Amino-9-benzyl-2-(1,3-dioxolan-2-yl-methyl)thio-8-hydroxypurine

Reaction equation

[Br:26][CH2:27][CH:28]1[O:29][CH2:30][CH2:31][O:32]1.[C:20](=[O:21])([O-:22])[O-:23].[CH3:33][N:34]([CH3:35])[CH:36]=[O:37].[K+:24].[K+:25].[NH2:1][c:2]1[c:3]2[n:4][c:5]([OH:19])[n:6]([CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[c:7]2[n:8][c:9]([SH:11])[n:10]1>>[NH2:1][c:2]1[c:3]2[n:4][c:5]([OH:19])[n:6]([CH2:12][c:13]3[cH:14][cH:15][cH:16][cH:17][cH:18]3)[c:7]2[n:8][c:9]([S:11][CH2:27][CH:28]2[O:29][CH2:30][CH2:31][O:32]2)[n:10]1

Participants

Reactant 5

HCID 813Potassium Cation2×

HCID 6228Dimethylformamide

HCID 19660Carbonate Ion

HCID 780681,3-Dioxolane, 2-(bromomethyl)-

HCID 1785090596-Amino-9-benzyl-8-hydroxy-2-mercaptopurine

Product 1

HCID 1785090406-Amino-9-benzyl-2-(1,3-dioxolan-2-yl-methyl)thio-8-hydroxypurine

Sources & evidence

ORD record: ord-34a7ef5257054732822244d4785adbe7
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

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