Cyanogen Bromide → 4-((1R,2S)-2-{2-[4-(ethylsulfonyl)-3-fluorophenoxy]ethyl}cyclopropyl)piperidine-1-carbonitrile
Reaction equation
[CH2:1]([S:3]([C:6]1[CH:23]=[CH:22][C:9]([O:10][CH2:11][CH2:12][C@@H:13]2[CH2:15][C@@H:14]2[CH:16]2[CH2:21][CH2:20][NH:19][CH2:18][CH2:17]2)=[CH:8][C:7]=1[F:24])(=[O:5])=[O:4])[CH3:2].C(=O)([O-])[O-].[K+].[K+].[N:31]#[C:32]Br>C(Cl)(Cl)Cl>[CH2:1]([S:3]([C:6]1[CH:23]=[CH:22][C:9]([O:10][CH2:11][CH2:12][C@@H:13]2[CH2:15][C@@H:14]2[CH:16]2[CH2:21][CH2:20][N:19]([C:32]#[N:31])[CH2:18][CH2:17]2)=[CH:8][C:7]=1[F:24])(=[O:5])=[O:4])[CH3:2]Participants
5
