Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 185249Generated: October 27, 2026

Dimethylformamide → 2-{4-[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-ylmethoxy]-phenoxy}-2-methyl-propionic acid ethyl ester

https://huagongshe.com/reaction/185249

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDimethylformamideHCID 6228—
ReactantCarbonate IonHCID 19660—
ReactantCesium cationHCID 104967—
ReactantEthyl 2-(4-hydroxyphenoxy)-2-methylpropanoateHCID 181741—
Reactant5-Chloromethyl-4-cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidineHCID 21935960—
Product2-{4-[4-Cyclopropyl-2-(4-trifluoromethyl-phenyl)-pyrimidin-5-ylmethoxy]-phenoxy}-2-methyl-propionic acid ethyl esterHCID 67072398—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (6/10)
ORD IDord-1c140e5f13a049a4877c50d24ea7baa0
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (6/10)