Hydrochloric Acid → 2-Methylsulfonyl-5-hydrazinopyrimidine hydrochloride

Reaction equation

[CH3:1][S:2]([C:5]1[N:10]=[CH:9][C:8]([NH:11][NH2:12])=[CH:7][N:6]=1)(=[O:4])=[O:3].[ClH:13]>>[ClH:13].[CH3:1][S:2]([C:5]1[N:10]=[CH:9][C:8]([NH:11][NH2:12])=[CH:7][N:6]=1)(=[O:4])=[O:3]

Participants

Reactant 2

HCID 313Hydrochloric Acid

HCID 12509326HCID 12509326, compound

Product 1

HCID 186240862-Methylsulfonyl-5-hydrazinopyrimidine hydrochlorideYield 78%

Procedure

2-Methylsulfonyl-5-hydrazinopyrimidine (2.0 g, 0.011 mol, J. Vavrina et al., Collection Czechoslov. Chem. Commun., 37, 1721 (1972)) was treated with 10% methanolic HCl, and volatiles were removed by evaporation. The precipitate was collected by filtration to give 1.8 g (78%) of the title compound.

Workup

customwere removed by evaporation
filtrationThe precipitate was collected by filtration

Sources & evidence

ORD record: ord-9dc0d460c6304737a105661db5efb0fa
Source dataset: uspto-grants-2003_03
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06531492B1

Reaction notes

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