Hydrochloric Acid → 4-[2-(Dimethylamino)ethyl]aniline--hydrogen chloride (1/2)

HRID 1861919Notes

Reaction equation

HRID 1861919 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([CH2:10][CH2:11][N:12]([CH3:14])[CH3:13])=[CH:6][CH:5]=1)([O-])=O.[ClH:15]>O1CCOCC1>[ClH:15].[ClH:15].[NH2:1][C:4]1[CH:5]=[CH:6][C:7]([CH2:10][CH2:11][N:12]([CH3:13])[CH3:14])=[CH:8][CH:9]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 220557n,n-Dimethyl-2-(4-nitrophenyl)ethanamine

Product 1

HCID 534078384-[2-(Dimethylamino)ethyl]aniline--hydrogen chloride (1/2)Yield 85%

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

Using the compound obtained in Example 97 as a starting material and after adding a solution of hydrogen chloride (4N) in 1,4-dioxane, the same procedure of Example 2 gave 2.37 g of the titled compound (yield, 85%).

Sources & evidence

ORD record
ord-70e02ef663034225aa2f79e8e43f9bb8
Source dataset
uspto-grants-2003_03
Patent number
US06534546B1

Reaction notes

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