Potassium Carbonate → 4-tert-Butyl-2-ethynyl-1-methyl-benzene
Reaction equation
[C:1]([C:5]1[CH:6]=[CH:7][C:8]([CH3:17])=[C:9]([C:11]#[C:12][Si](C)(C)C)[CH:10]=1)([CH3:4])([CH3:3])[CH3:2].C(=O)([O-])[O-].[K+].[K+]>CO>[C:1]([C:5]1[CH:6]=[CH:7][C:8]([CH3:17])=[C:9]([C:11]#[CH:12])[CH:10]=1)([CH3:4])([CH3:3])[CH3:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
Following general procedure F and using (5-tert-butyl-2-methyl-phenylethynyl)trimethyl-silane (Intermediate 109, 0.16 g, 0.66 mmol), methanol (5 mL) and potassium carbonate (0.05 g, 0.36 mmol), the title compound was obtained (0.08 g, 67%).
Sources & evidence
- ORD record
- ord-9e7f8a06fef84ea48283fe6c8e82d2d8
- Source dataset
- uspto-grants-2009_12
- Patent number
- US07638648B2
Reaction notes
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