Methyl iodide → HCID 68590834, compound
Reaction equation
[CH3:1][C:2]1[C:7]2[S:8][CH:9]=[CH:10][C:6]=2[CH2:5][CH2:4][N:3]=1.[CH3:11][I:12]>C(OCC)(=O)C>[I-:12].[CH3:11][N+:3]1[CH2:4][CH2:5][C:6]2[CH:10]=[CH:9][S:8][C:7]=2[C:2]=1[CH3:1]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 4.64 g (31 mmol) 7-methyl-4,5-dihydro-thieno[2,3-c]pyridine (prepared analogously to J.Am.Chem.Soc., 1951, 1257), 8.0 ml (128 mmol) methyl iodide and 20 ml of ethyl acetate is stirred for 15 min. The precipitate formed is suction filtered, washed with ethyl acetate and dried in vacuo.
Workup
- customprepared analogously to J.Am.Chem.Soc
- customThe precipitate formed
- filtrationfiltered
- washwashed with ethyl acetate
- customdried in vacuo
Sources & evidence
- ORD record
- ord-0843bf2fcfc94ff0ada02d33864cdc05
- Source dataset
- uspto-grants-2012_11
- Patent number
- US08309542B2
Reaction notes
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