Ammonia → (+/-)-Abscisic acid

HRID 1882183

Reaction equation

HRID 1882183 reaction equation
[CH3:1][C:2]1[C@:8]([OH:17])(/[CH:9]=[CH:10]/[C:11](/[CH3:16])=[CH:12]\[C:13]([OH:15])=[O:14])[C:7]([CH3:19])([CH3:18])[CH2:6][C:4](=[O:5])[CH:3]=1.[OH-].[K+].N.C([O-])(=O)/C=C/C=C/C.[K+]>O>[CH3:1][C:2]1[C:8]([OH:17])(/[CH:9]=[CH:10]/[C:11](/[CH3:16])=[CH:12]\[C:13]([OH:15])=[O:14])[C:7]([CH3:19])([CH3:18])[CH2:6][C:4](=[O:5])[CH:3]=1

Participants

6

Reactant 4

HCID 222AmmoniaHCID 14797Potassium HydroxideHCID 5280896Abscisic AcidHCID 23676745Potassium Sorbate

Product 1

HCID 5375199(+/-)-Abscisic acid

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

(S)-(+)-Abscisic acid (2.64 g of 95% purity) was suspended in 15 mL of deionized water containing 50 mg of Tween 20. One quarter of the theoretical amount of potassium hydroxide (250 microL of 10.0 molar aqueous solution) was added. The remainder of the neutralization was then carried out with concentrated aqueous ammonia solution, to give a clear solution of pH 7.1. Preservative (63 mg of potassium sorbate) was added, and it quickly dissolved. The solution was made up to 25 mL final volume to give a 10% by weight aqueous composition of abscisic acid as a mixture of the ammonium and potassium salts.

Workup

  1. customto give a clear solution of pH 7.1
  2. dissolutionit quickly dissolved

Sources & evidence

ORD record
ord-f2fd709f55464c6193b3cb8ac0b56f91
Source dataset
uspto-grants-2012_11
Patent number
US08318976B2

Linked notes

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