Acrylamide → n-Butylacrylate Acrylamide

HRID 1884797

Reaction equation

HRID 1884797 reaction equation
[CH2:1]([O:5][C:6](=[O:9])[CH:7]=[CH2:8])[CH2:2][CH2:3][CH3:4].[C:10]([NH2:14])(=[O:13])[CH:11]=[CH2:12]>C(O)(C)C>[CH2:1]([O:5][C:6](=[O:9])[CH:7]=[CH2:8])[CH2:2][CH2:3][CH3:4].[C:10]([NH2:14])(=[O:13])[CH:11]=[CH2:12]

Participants

4

Reactant 2

HCID 6579AcrylamideHCID 8846Butyl Acrylate

Product 1

HCID 86584089n-Butylacrylate Acrylamide

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Conditions

Temperature
75 °C

Procedure

To a 500 mL round-bottom, three-neck flask fitted with a thermocouple, reflux condenser, and septum was added 150 mL of isopropanol followed by 16.13 g of a 50% aqueous solution of 2-trimethylammoniumethylacrylate chloride, 8.06 g of n-butylacrylate, and 8.06 g of acrylamide. The solution was purged with nitrogen for 1 hour and 0.5 g AIBN was added. The mixture was purged for ˜15 minutes until all of the AIBN dissolved. The solution was heated to 75° C. under nitrogen for 16 hours.

Workup

  1. customTo a 500 mL round-bottom, three-neck flask fitted with a thermocouple
  2. temperaturereflux condenser
  3. customThe solution was purged with nitrogen for 1 hour
  4. addition0.5 g AIBN was added
  5. customThe mixture was purged for ˜15 minutes until all of the AIBN
  6. dissolutiondissolved

Sources & evidence

ORD record
ord-82ce0e7410c143d8b914c37306e01457
Source dataset
uspto-grants-2004_07
Patent number
US06767549B2

Linked notes

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