Tetrahydrofuran → 2-[(2,2,2-Trifluoro-acetylamino)-methyl]-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester
Reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15](=[O:16])[N:17]1[CH:18]([CH2:23][NH2:24])[CH:19]2[CH2:20][CH:21]2[CH2:22]1.[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[F:1][C:2]([C:3]([O:5][CH2:4][CH3:6])=[O:7])([F:8])[F:9]>>[F:1][C:2]([C:3](=[O:5])[NH:24][CH2:23][CH:18]1[N:17]([C:15]([O:14][C:10]([CH3:11])([CH3:12])[CH3:13])=[O:16])[CH2:22][CH:21]2[CH:19]1[CH2:20]2)([F:8])[F:9]Participants
4
Sources & evidence
- ORD record
- ord-c8587f475cf34f419653da8ee08ed51e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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