methyl {4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl}carbamate sulphinyldimethane → Nelociguat
Reaction equation
S(C)(C)=O.[NH2:5][C:6]1[C:11]([NH:12][C:13](=[O:16])[O:14][CH3:15])=[C:10]([NH2:17])[N:9]=[C:8]([C:18]2[C:26]3[C:21](=[N:22][CH:23]=[CH:24][CH:25]=3)[N:20]([CH2:27][C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=3[F:34])[N:19]=2)[N:7]=1>C(OCC)(=O)C.C(O)C>[NH2:5][C:6]1[C:11]([NH:12][C:13](=[O:16])[O:14][CH3:15])=[C:10]([NH2:17])[N:9]=[C:8]([C:18]2[C:26]3[C:21](=[N:22][CH:23]=[CH:24][CH:25]=3)[N:20]([CH2:27][C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][C:29]=3[F:34])[N:19]=2)[N:7]=1Participants
4
Reactant 1
Product 1
Reagents, catalysts & solvents 2
Conditions
- Temperature
- 73.5 °C