Chloroform → 2-(3-fluoro-4-methylphenyl)-1H-isoindole-1,3(2H)-dione

HRID 188921

Reaction equation

HRID 188921 reaction equation
[CH3:21][CH2:22][N:23]([CH2:24][CH3:25])[CH2:26][CH3:27].[CH:28]([Cl:29])([Cl:30])[Cl:31].[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[CH3:9].[O:10]=[C:11]1[O:12][C:13](=[O:14])[c:15]2[cH:16][cH:17][cH:18][cH:19][c:20]21>>[F:1][c:2]1[cH:3][c:4]([N:5]2[C:11](=[O:10])[c:20]3[c:15]([cH:16][cH:17][cH:18][cH:19]3)[C:13]2=[O:12])[cH:6][cH:7][c:8]1[CH3:9]

Participants

5

Reactant 4

HCID 6212ChloroformHCID 6811Phthalic AnhydrideHCID 8471TriethylamineHCID 99573-Fluoro-4-methylaniline

Product 1

HCID 6833332-(3-fluoro-4-methylphenyl)-1H-isoindole-1,3(2H)-dione

Sources & evidence

ORD record
ord-db321dc93db04156b929282e55c7df23
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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