4'-{[6-ethyl-3-(1-methyl-2-oxoethyl)-2,4-dioxo-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl]methyl}biphenyl-2-carbonitrile → 4'-{[6-ethyl-3-[2-hydroxy-2-(4-methoxyphenyl)-1-methylethyl]-2,4-dioxo-3,4-dihydrothieno[2,3-d]pyrimidin-1(2H)-yl]methyl}biphenyl-2-carbonitrile

Reaction equation

[CH2:1]([C:3]1[S:32][C:6]2[N:7]([CH2:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]4[C:25]([C:30]#[N:31])=[CH:26][CH:27]=[CH:28][CH:29]=4)=[CH:20][CH:19]=3)[C:8](=[O:16])[N:9]([CH:12]([CH3:15])[CH:13]=[O:14])[C:10](=[O:11])[C:5]=2[CH:4]=1)[CH3:2].[CH3:33][O:34][C:35]1[CH:40]=[CH:39][C:38]([Mg]Br)=[CH:37][CH:36]=1>O1CCCC1>[CH2:1]([C:3]1[S:32][C:6]2[N:7]([CH2:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]4[C:25]([C:30]#[N:31])=[CH:26][CH:27]=[CH:28][CH:29]=4)=[CH:20][CH:19]=3)[C:8](=[O:16])[N:9]([CH:12]([CH3:15])[CH:13]([OH:14])[C:38]3[CH:39]=[CH:40][C:35]([O:34][CH3:33])=[CH:36][CH:37]=3)[C:10](=[O:11])[C:5]=2[CH:4]=1)[CH3:2]