Hydrazine → 2-Hydrazinyl-4-methylquinoline

HRID 1892274Notes

Reaction equation

HRID 1892274 reaction equation
Cl[C:2]1[CH:11]=[C:10]([CH3:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1.[NH2:13][NH2:14]>>[NH:13]([C:2]1[CH:11]=[C:10]([CH3:12])[C:9]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[N:3]=1)[NH2:14]

Participants

3

Reactant 2

HCID 9321HydrazineHCID 694492-Chloro-4-methylquinoline

Product 1

HCID 8181952-Hydrazinyl-4-methylquinoline

Procedure

A solution of 2-chloro-4-methylquinoline (1.00 g, 5.63 mmol) in NH2NH2 was reacted as outlined in Scheme 1 above to give the title compound which was used in the next step without further purification.

Sources & evidence

ORD record
ord-f6aff0452003447392edc8e7e632147b
Source dataset
uspto-grants-2013_08
Patent number
US08507682B2

Reaction notes

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