Methanol → Fmoc-aminocyclohexane carboxylic acid

HRID 189793

Reaction equation

HRID 189793 reaction equation
[C:11](=[O:12])([O:13][CH2:14][CH:15]1[c:16]2[cH:17][cH:18][cH:19][cH:20][c:21]2-[c:22]2[cH:23][cH:24][cH:25][cH:26][c:27]21)[Cl:28].[CH3:49][OH:50].[CH:29]([N:30]([CH:31]([CH3:32])[CH3:33])[CH2:34][CH3:35])([CH3:36])[CH3:37].[Cl:46][CH2:47][Cl:48].[NH2:1][C:2]1([C:8](=[O:9])[OH:10])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7]1.[Na+:39].[O:40]1[CH2:41][CH2:42][O:43][CH2:44][CH2:45]1.[OH-:38]>>[NH2:1][C:2]1([C:8](=[O:9])[OH:10])[CH:3]([C:11](=[O:12])[O:13][CH2:14][CH:15]2[c:16]3[cH:17][cH:18][cH:19][cH:20][c:21]3-[c:22]3[cH:23][cH:24][cH:25][cH:26][c:27]32)[CH2:4][CH2:5][CH2:6][CH2:7]1

Participants

9

Reactant 8

HCID 887MethanolHCID 923Sodium ionHCID 961HydroxideHCID 13661-Aminocyclohexanecarboxylic acidHCID 6344DichloromethaneHCID 312751,4-DioxaneHCID 343679-Fluorenylmethyl chloroformateHCID 81531Diisopropylethylamine

Product 1

HCID 56923993Fmoc-aminocyclohexane carboxylic acid

Sources & evidence

ORD record
ord-647718148fa648b78aabbc7ee5d9290b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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