Hydrochloric Acid → 5-Hydroxyindan-1,2,3-trione, monohydrate

Reaction equation

Br[CH:2]1[C:10](=[O:11])[C:9]2[C:4](=[CH:5][CH:6]=[C:7]([OH:12])[CH:8]=2)[C:3]1=[O:13].Cl.CS(C)=[O:17]>>[OH2:11].[OH:12][C:7]1[CH:8]=[C:9]2[C:4](=[CH:5][CH:6]=1)[C:3](=[O:13])[C:2](=[O:17])[C:10]2=[O:11]

Participants

Reactant 3

HCID 313Hydrochloric Acid

HCID 679Dimethyl Sulfoxide

HCID 190342852-Bromo-5-hydroxyindan-1,3-dione

Product 1

HCID 218031995-Hydroxyindan-1,2,3-trione, monohydrate

Procedure

A solution of 0.01 mol of 2-bromo-5-hydroxyindan-1,3-dione in 10 ml dimethyl sulphoxide was heated to 80° C. for 30 minutes. 50 ml of a 1N hydrochloric acid solution was added, after which heating was continued for 30 minutes. The oily suspension obtained after cooling was extracted with ethyl ether. The organic phase was washed in water and dried over magnesium sulphate.