1,2-Epoxyhexadecane → 3-(2-Hydroxyhexadecyloxy)-2-methoxypropyl tetrahydropyranyl ether

HRID 1906049

Reaction equation

HRID 1906049 reaction equation
[O:1]1[CH:3]([CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17])[CH2:2]1.[O:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH:19]1[O:24][CH2:25][CH:26]([CH2:29][OH:30])[O:27][CH3:28]>>[O:18]1[CH2:23][CH2:22][CH2:21][CH2:20][CH:19]1[O:24][CH2:25][CH:26]([O:27][CH3:28])[CH2:29][O:30][CH2:2][CH:3]([OH:1])[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH3:17]

Participants

3

Reactant 2

HCID 237411,2-EpoxyhexadecaneHCID 13563077HCID 13563077, compound

Product 1

HCID 202138223-(2-Hydroxyhexadecyloxy)-2-methoxypropyl tetrahydropyranyl etherYield 53.2%

Procedure

The epoxide (9) (4.8 g, 20 mmoles) as obtained in Example 4-1 was reacted with 7.6 g (40 mmoles) of 2-methylglycerol monotetrahydropyranyl ether in the same manner as Example 1-2 to give 4.58 g (53.2%) of the desired compound (10).

Sources & evidence

ORD record
ord-5d5a4e6881d74511a5e0214a95db749f
Source dataset
uspto-grants-1987_03
Patent number
US04649203

Linked notes

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