Acetic Acid → N-(biphenyl-4-ylmethyl)-5-bromopyrazin-2-amine

HRID 193025

Reaction equation

HRID 193025 reaction equation
[CH3:27][C:28](=[O:29])[OH:30].[Cl:23][CH:24]([Cl:25])[CH3:26].[Cl:31][CH2:32][Cl:33].[NH2:15][c:16]1[n:17][cH:18][c:19]([Br:22])[n:20][cH:21]1.[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([CH:11]=[O:12])[cH:13][cH:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1(-[c:7]2[cH:8][cH:9][c:10]([CH2:11][NH:15][c:16]3[n:17][cH:18][c:19]([Br:22])[n:20][cH:21]3)[cH:13][cH:14]2)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 176Acetic AcidHCID 6344DichloromethaneHCID 63651,1-DichloroethaneHCID 76689(1,1'-Biphenyl)-4-carboxaldehydeHCID 5995392-Amino-5-bromopyrazine

Product 1

HCID 86614306N-(biphenyl-4-ylmethyl)-5-bromopyrazin-2-amine

Sources & evidence

ORD record
ord-818ca92786434ef2800c5da1cb71c8f2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…