Acetic Anhydride → 2-Ethylamino-4-methylcarbonylamino-6-methyl-5-[3-(4-chlorophenyl)-1-butenyl]pyrimidine
Reaction equation
[CH2:1]([NH:3][C:4]1[N:9]=[C:8]([NH2:10])[C:7]([CH:11]=[CH:12][CH:13]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)[CH3:14])=[C:6]([CH3:22])[N:5]=1)[CH3:2].[C:23](OC(=O)C)(=[O:25])[CH3:24]>CN(C)C1C=CN=CC=1>[CH2:1]([NH:3][C:4]1[N:9]=[C:8]([NH:10][C:23]([CH3:24])=[O:25])[C:7]([CH:11]=[CH:12][CH:13]([C:15]2[CH:20]=[CH:19][C:18]([Cl:21])=[CH:17][CH:16]=2)[CH3:14])=[C:6]([CH3:22])[N:5]=1)[CH3:2]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
This compound is prepared in a manner analogous to that of Example 8, using 0.32 gram (0.001 mole) 2-ethylamino-4-amino-6-methyl-5-[3-(4-chlorophenyl)-1-butenyl]pyrimidine (Compound 47-prepared in Example 7) and 0.01 gram (catalyst) of 4-dimethylaminopyridine in 5 mL of acetic anhydride, yielding 2-ethylamino-4-methylcarbonylamino-6-methyl-5-[3-(4-chlorophenyl)-1-butenyl]pyrimidine.