Hydrochloric Acid → 1-Piperazineacetic acid, 4-(4-pyridinyl)-, hydrochloride (1:2)
Reaction equation
[ClH:1].Cl.[N:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][C:16]([O:18]C)=[O:17])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1.Cl>>[ClH:1].[ClH:1].[N:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:14][CH2:13][N:12]([CH2:15][C:16]([OH:18])=[O:17])[CH2:11][CH2:10]2)=[CH:7][CH:8]=1Participants
3
Procedure
Prepared from methyl [4-(4-pyridyl)-piperazin-1-yl]acetate dihydrochloride and semiconcentrated hydrochloric acid analogously to Example IIb.
Sources & evidence
- ORD record
- ord-f29db7952c6e41d4a9bdf661c798c7d0
- Source dataset
- uspto-grants-1997_12
- Patent number
- US05700801
Reaction notes
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