Ethyl Acetate → 4-methyl-N-(2,2,2-trifluoro-1-hydroxyethyl)benzamide

HRID 195063

Reaction equation

HRID 195063 reaction equation
[CH2:1]([O:2][CH:4]([C:5]([F:6])([F:7])[F:8])[OH:9])[CH3:3].[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31].[O:20]1[CH2:21][CH2:22][O:23][CH2:24][CH2:25]1.[c:10]1([CH3:19])[cH:11][cH:12][c:13]([C:16](=[O:17])[NH2:18])[cH:14][cH:15]1>>[CH:4]([C:5]([F:6])([F:7])[F:8])([OH:9])[NH:18][C:16]([c:13]1[cH:12][cH:11][c:10]([CH3:19])[cH:15][cH:14]1)=[O:17]

Participants

5

Reactant 4

HCID 8857Ethyl AcetateHCID 9897Ethanol, 1-ethoxy-2,2,2-trifluoro-HCID 312751,4-DioxaneHCID 692744-Methylbenzamide

Product 1

HCID 121503224-methyl-N-(2,2,2-trifluoro-1-hydroxyethyl)benzamide

Sources & evidence

ORD record
ord-06848c2d6102444aa34c63e105b1adc8
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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