[CH3:1][O:2][CH:3](OC)[C:4]([O:6][CH3:7])=[O:5].C([Cl:13])(=O)C.[C:14]1([P:20]([C:27]2[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=2)[C:21]2[CH:26]=[CH:25][CH:24]=[CH:23][CH:22]=2)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>II>[Cl-:13].[CH3:1][O:2][CH:3]([P+:20]([C:21]1[CH:22]=[CH:23][CH:24]=[CH:25][CH:26]=1)([C:27]1[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=1)[C:14]1[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=1)[C:4]([O:6][CH3:7])=[O:5]25 g (186 mmol) of methyl dimethoxyacetate is added to 27 ml (215 mmol) of acetyl chloride at room temperature. 0.1 g (0.2% molar) of iodine is added and then the reaction mixture is stirred at 55° C. for 16 hours. The excess of acetyl chloride is evaporated under vacuum, then the residue is dissolved in 100 ml of dichloromethane. 49 g (204 mmol) of triphenylphosphine is added and then the reaction mixture is stirred at 37° C. for 3 hours. The solvents are evaporated and the residue is crystallized in diisopropyl ether. 70 g (88%) of (methoxy-methoxycarbonyl-methyl)-triphenyl-phosphonium chloride is obtained.
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