HCID 54370181, compound → HCID 10451888, compound
Reaction equation
[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([N:8]=[C:9]([O:16]C)[C:10]([O:14]C)=[N:11]2)=[C:6]([CH2:18][N:19]([CH2:28][CH3:29])[C@H:20]([P:22](=[O:27])([O:25]C)[O:23]C)[CH3:21])[CH:5]=1)([O-:3])=[O:2]>Cl>[N+:1]([C:4]1[CH:13]=[C:12]2[C:7]([NH:8][C:9](=[O:16])[C:10](=[O:14])[NH:11]2)=[C:6]([CH2:18][N:19]([CH2:28][CH3:29])[C@H:20]([P:22](=[O:23])([OH:27])[OH:25])[CH3:21])[CH:5]=1)([O-:3])=[O:2]Participants
3
Reactant 1
Product 1
Reagents, catalysts & solvents 1
Procedure
4.24 g (9.9 mmol) of dimethyl (R)-N-(7-nitro-2,3-dimethoxyquinoxalin-5-ylmethyl)-α-ethylaminoethylphosphonate are stirred for 19 hours in 80 ml of 6N hydrochloric acid. The reaction mixture is evaporated and the residue is slurried with water. The title compound is obtained as a solid of m.p.=218° C. (dec.).
Workup
- customThe reaction mixture is evaporated