Benzene → 1-Chloro-5-methoxy-2,6-dimethylheptane
Reaction equation
O[CH2:2][CH:3]([CH3:12])[CH2:4][CH2:5][CH:6]([O:10][CH3:11])[CH:7]([CH3:9])[CH3:8].S(Cl)([Cl:15])=O.C1C=CC=CC=1>CN(C)C=O>[Cl:15][CH2:2][CH:3]([CH3:12])[CH2:4][CH2:5][CH:6]([O:10][CH3:11])[CH:7]([CH3:9])[CH3:8]Participants
5
Reactant 3
Product 1
Reagents, catalysts & solvents 1
Procedure
A mixture of 3.4 g. of 1-hydroxy-5-methoxy-2,6-dimethylheptane and 3 g. of thionyl chloride and 60 ml. of dry benzene is treated with 0.2 ml. of dry dimethylformamide and then refluxed for 6 hours. After cooling, the mixture is decanted and 1-chloro-5-methoxy-2,6-dimethylheptane isolated by filtration through silica gel and distillation.
Workup
- additionA mixture of 3.4 g
- temperatureAfter cooling
- customthe mixture is decanted
Sources & evidence
- ORD record
- ord-9e28c3b1838e43e1b18d58eaed4a4ad2
- Source dataset
- uspto-grants-1976_12
- Patent number
- US04000174
Reaction notes
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