Hydrochloric Acid → (RS)-Clopidogrel

HRID 197528

Reaction equation

HRID 197528 reaction equation
[C:31](=[O:32])([OH:33])[O-:34].[CH3:36][C:37]#[N:38].[CH3:9][O:10][C:11]([CH:12]([N:13]1[CH2:14][c:15]2[c:16]([s:20][cH:21][cH:22]2)[CH:17]([OH:19])[CH2:18]1)[c:23]1[c:24]([Cl:29])[cH:25][cH:26][cH:27][cH:28]1)=[O:30].[Cl:3][Si:4]([CH3:5])([CH3:6])[CH3:7].[ClH:8].[I-:2].[Na+:1].[Na+:35]>>[CH3:9][O:10][C:11]([CH:12]([N:13]1[CH2:14][c:15]2[c:16]([s:20][cH:21][cH:22]2)[CH2:17][CH2:18]1)[c:23]1[c:24]([Cl:29])[cH:25][cH:26][cH:27][cH:28]1)=[O:30]

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 769Bicarbonate IonHCID 923Sodium ion2×HCID 6342AcetonitrileHCID 6397ChlorotrimethylsilaneHCID 30165Iodide IonHCID 13938216(+/-) Methyl alpha-(7-Hydroxy-4,5,6,7-tetrahydro-5-thieno[3,2-c]pyridyl)-o-chlorophenylacetate

Product 1

HCID 2806(RS)-Clopidogrel

Sources & evidence

ORD record
ord-b133dd6774d04039a7429f32b0d515c2
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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