Hydrochloric Acid → 2',4',6'-Triiodo-3'-ethyl-3-nitrobiphenyl-4-carboxylic acid

HRID 1976506Notes

Reaction equation

HRID 1976506 reaction equation
[I:1][C:2]1[C:7]([C:8](=O)[CH3:9])=[C:6]([I:11])[CH:5]=[C:4]([I:12])[C:3]=1[C:13]1[CH:18]=[CH:17][C:16]([C:19]([OH:21])=[O:20])=[C:15]([N+:22]([O-:24])=[O:23])[CH:14]=1.Cl>>[I:1][C:2]1[C:7]([CH2:8][CH3:9])=[C:6]([I:11])[CH:5]=[C:4]([I:12])[C:3]=1[C:13]1[CH:18]=[CH:17][C:16]([C:19]([OH:21])=[O:20])=[C:15]([N+:22]([O-:24])=[O:23])[CH:14]=1

Participants

3

Reactant 2

HCID 313Hydrochloric AcidHCID 223419962',4',6'-Triiodo-3'-acetyl-3-nitrobiphenyl-4-carboxylic acid

Product 1

HCID 223419932',4',6'-Triiodo-3'-ethyl-3-nitrobiphenyl-4-carboxylic acid

Procedure

2′,4′,6′-triiodo-3′-acetyl-3-nitrobiphenyl-4-carboxylic acid (12) is then reacted with a zinc mercury amalgam and hydrochloric acid and heated to yield 2′,4′,6′-triiodo-3′-ethyl-3-nitrobiphenyl-4-carboxylic acid (13).

Workup

  1. temperatureheated

Sources & evidence

ORD record
ord-eb7372178bea48b68154be767e6ba1ca
Source dataset
uspto-grants-2001_05
Patent number
US06226352B1

Reaction notes

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