Methyl iodide → Ethyl 1,4-dibenzyl-2-methylpiperazine-2-carboxylate

HRID 198487

Reaction equation

HRID 198487 reaction equation
[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH:9]([C:21](=[O:22])[O:23][CH2:24][CH3:25])[CH2:10][N:11]([CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH3:27][CH:28]([N-:29][CH:30]([CH3:31])[CH3:32])[CH3:33].[CH3:34][I:35].[Li+:26]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[C:9]([C:21](=[O:22])[O:23][CH2:24][CH3:25])([CH3:27])[CH2:10][N:11]([CH2:14][c:15]2[cH:16][cH:17][cH:18][cH:19][cH:20]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 6328Methyl iodideHCID 28486Lithium ionHCID 2736402Ethyl 1,4-dibenzylpiperazine-2-carboxylateHCID 5062348Diisopropylamide

Product 1

HCID 58855869Ethyl 1,4-dibenzyl-2-methylpiperazine-2-carboxylate

Sources & evidence

ORD record
ord-090a29e59f594fe6974cccfeff731676
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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