Dimethylformamide → 4-[4-(4-Acetyl-3-methyl-phenoxy)-pyrazolo[3,4-d]pyrimidin-1-yl]-piperidine-1-carboxylic acid tert-butyl ester

HRID 198580

Reaction equation

HRID 198580 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([n:14]2[n:15][cH:16][c:17]3[c:18]2[n:19][cH:20][n:21][c:22]3[Cl:23])[CH2:12][CH2:13]1.[CH3:35][N:36]([CH3:37])[CH:38]=[O:39].[OH:24][c:25]1[cH:26][c:27]([CH3:34])[c:28]([C:31]([CH3:32])=[O:33])[cH:29][cH:30]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([n:14]2[n:15][cH:16][c:17]3[c:18]2[n:19][cH:20][n:21][c:22]3[O:24][c:25]2[cH:26][c:27]([CH3:34])[c:28]([C:31]([CH3:32])=[O:33])[cH:29][cH:30]2)[CH2:12][CH2:13]1

Participants

4

Reactant 3

HCID 6228DimethylformamideHCID 701334-Hydroxy-2-methylacetophenoneHCID 57964905Tert-butyl 4-(4-chloro-1H-pyrazolo[3,4-D]pyrimidin-1-YL)piperidine-1-carboxylate

Product 1

HCID 579650064-[4-(4-Acetyl-3-methyl-phenoxy)-pyrazolo[3,4-d]pyrimidin-1-yl]-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-ed077f4f60ab40488ca6820ca869f8f4
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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