Sodium methanethiolate → HCID 18434372, compound
Reaction equation
[Br:1][C:2]1[CH:7]=[CH:6][C:5](CBr)=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1.[CH3:13][S-:14].[Na+]>O1CCCC1>[Br:1][C:2]1[CH:7]=[CH:6][C:5]([S:14][CH3:13])=[C:4]([N+:10]([O-:12])=[O:11])[CH:3]=1Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
A suspension of 4-bromo-1-(bromomethyl)-2-nitrobenzene (1.0 g) and sodium methanethiolate (0.285 g) in tetrahydrofuran (20 ml) was stirred under nitrogen for 60 h. The solvent was evaporated, chloroform (50 ml) was added and the rsidual solid was removed by filtration. The filtrate was comncentrated under vacuum to give the title compound (0.89 g).
Workup
- customThe solvent was evaporated
- additionchloroform (50 ml) was added
- customthe rsidual solid was removed by filtration
Sources & evidence
- ORD record
- ord-9f04f6de723e4ac1822b9b8dab7cc130
- Source dataset
- uspto-grants-2010_01
- Patent number
- US07642276B2
Reaction notes
Loading…