Formaldehyde → 2-(2-Tert-butoxycarbonylamino-pyridin-4-ylmethyl)-acrylic acid ethyl ester

HRID 200531

Reaction equation

[CH2:1]([NH:2][CH2:3][CH3:4])[CH3:5].[CH2:30]=[O:31].[CH2:32]([Cl:33])[Cl:34].[CH2:6]([CH3:7])[O:8][C:9]([CH:10]([C:11]([OH:12])=[O:13])[CH2:14][c:15]1[cH:16][c:17]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[n:18][cH:19][cH:20]1)=[O:29]>>[CH2:6]([CH3:7])[O:8][C:9]([C:10](=[CH2:11])[CH2:14][c:15]1[cH:16][c:17]([NH:21][C:22](=[O:23])[O:24][C:25]([CH3:26])([CH3:27])[CH3:28])[n:18][cH:19][cH:20]1)=[O:29]

Participants

Reactant 4

HCID 712Formaldehyde

HCID 6344Dichloromethane

HCID 8021Diethylamine

HCID 545486422-(2-Tert-butoxycarbonylamino-pyridin4-ylmethyl)-malonic acid monoethyl ester

Product 1

HCID 544852162-(2-Tert-butoxycarbonylamino-pyridin-4-ylmethyl)-acrylic acid ethyl ester

Sources & evidence

ORD record: ord-f5ac0a8c147d49beb24eca4f4ee6a81d
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Linked notes

Loading…