Hydrochloric Acid → [5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[2-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone

HRID 200559

Reaction equation

HRID 200559 reaction equation
[CH3:16][S:17](=[O:18])(=[O:19])[c:20]1[cH:21][cH:22][c:23]([O:29][CH:30]([C:31]([F:32])([F:33])[F:34])[CH3:35])[c:24]([C:25](=[O:26])[OH:27])[cH:28]1.[ClH:1].[F:2][C:3]([c:4]1[n:5][c:6]2[c:11]([cH:12][cH:13]1)[CH2:10][NH:9][CH2:8][CH2:7]2)([F:14])[F:15]>>[F:2][C:3]([c:4]1[n:5][c:6]2[c:11]([cH:12][cH:13]1)[CH2:10][N:9]([C:25]([c:24]1[c:23]([O:29][CH:30]([C:31]([F:32])([F:33])[F:34])[CH3:35])[cH:22][cH:21][c:20]([S:17]([CH3:16])(=[O:18])=[O:19])[cH:28]1)=[O:26])[CH2:8][CH2:7]2)([F:14])[F:15]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 211003065-Methylsulfonyl-2-(2,2,2-trifluoro-1-methylethoxy)benzoic acidHCID 534719842-(Trifluoromethyl)-5,6,7,8-tetrahydro-1,6-naphthyridine

Product 1

HCID 72389661[5-methylsulfonyl-2-(1,1,1-trifluoropropan-2-yloxy)phenyl]-[2-(trifluoromethyl)-7,8-dihydro-5H-1,6-naphthyridin-6-yl]methanone

Sources & evidence

ORD record
ord-ed054c5271db48f289e17c982c13ce4f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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