Formic acid (ammonium salt) → (S)-1-(5-Fluoro-2-methoxyphenyl)ethan-1-ol

HRID 2005819

Reaction equation

HRID 2005819 reaction equation
[CH3:1][O:2][c:3]1[c:9]([C:10]([CH3:12])=[O:11])[cH:8][c:6]([F:7])[cH:5][cH:4]1.N.OC=O>>[CH3:1][O:2][c:3]1[c:9]([C@@H:10]([OH:11])[CH3:12])[cH:8][c:6]([F:7])[cH:5][cH:4]1

Participants

5

Reactant 2

HCID 10904Formic acid (ammonium salt)HCID 27373561-(5-Fluoro-2-methoxyphenyl)ethan-1-one

Product 1

HCID 14928684(S)-1-(5-Fluoro-2-methoxyphenyl)ethan-1-ol

Reagents, catalysts & solvents 2

HCID 6344DichloromethaneSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
50 °C

Sources & evidence

ORD record
ord-5fd212a6b13b429ead4acfe5f5050d04
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Linked notes

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