Tetrahydrofuran → 2-(2-Bromo-4-methylphenyl)-1,3-difluoropropan-2-ol

Reaction equation

[Br:1][c:2]1[c:3]([I:9])[cH:4][cH:5][c:6]([CH3:8])[cH:7]1.[CH2:16]1[O:17][CH2:18][CH2:19][CH2:20]1.[F:10][CH2:11][C:12]([CH2:13][F:14])=[O:15]>>[Br:1][c:2]1[c:3]([C:12]([CH2:11][F:10])([CH2:13][F:14])[OH:15])[cH:4][cH:5][c:6]([CH3:8])[cH:7]1

Participants

Reactant 3

HCID 8028Tetrahydrofuran

HCID 2283971,3-Difluoroacetone

HCID 6266343-Bromo-4-iodotoluene

Product 1

HCID 726983412-(2-Bromo-4-methylphenyl)-1,3-difluoropropan-2-ol

Sources & evidence

ORD record: ord-00ad56c1b3b84fff97cb78e3aaec55da
Source dataset: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

Reaction notes

Loading…