Water → 6-Bromo-2-(2-fluoro-phenyl)-4-pyrrolo[3,2-c]pyridin-1-yl-quinazoline

HRID 200960Notes

Reaction equation

HRID 200960 reaction equation
[Br:1][c:2]1[cH:3][c:4]2[c:5]([Cl:19])[n:6][c:7](-[c:12]3[c:13]([F:18])[cH:14][cH:15][cH:16][cH:17]3)[n:8][c:9]2[cH:10][cH:11]1.[C:29](=[O:30])([O-:31])[O-:32].[CH:36]([N:37]([CH3:38])[CH3:39])=[O:40].[Cs+:33].[Cs+:34].[OH2:35].[nH:20]1[cH:21][cH:22][c:23]2[cH:24][n:25][cH:26][cH:27][c:28]12>>[Br:1][c:2]1[cH:3][c:4]2[c:5](-[n:20]3[cH:21][cH:22][c:23]4[cH:24][n:25][cH:26][cH:27][c:28]34)[n:6][c:7](-[c:12]3[c:13]([F:18])[cH:14][cH:15][cH:16][cH:17]3)[n:8][c:9]2[cH:10][cH:11]1

Participants

7

Reactant 6

HCID 962WaterHCID 6228DimethylformamideHCID 92205-AzaindoleHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 184406506-Bromo-4-chloro-2-(2-fluorophenyl)quinazoline

Product 1

HCID 103647546-Bromo-2-(2-fluoro-phenyl)-4-pyrrolo[3,2-c]pyridin-1-yl-quinazoline

Sources & evidence

ORD record
ord-98be23f7ab8440feab1bb8dbc0a66753
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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