6-Chloroquinoline → HCID 122392050, compound

HRID 2013373

Reaction equation

HRID 2013373 reaction equation
[CH3:1][O:2][c:3]1[n:8][cH:7][c:6](S(O)=O)[cH:5][cH:4]1.Cl[c:9]1[cH:18][c:17]([c:12]2[cH:11][cH:10]1)[cH:16][cH:15][cH:14][n:13]2>>[CH3:1][O:2][c:3]1[n:8][cH:7][c:6]([c:9]2[cH:18][c:17]([c:12]3[cH:11][cH:10]2)[cH:16][cH:15][cH:14][n:13]3)[cH:5][cH:4]1

Participants

8

Reactant 2

HCID 691636-ChloroquinolineHCID 178492810HCID 178492810, compound

Product 1

HCID 122392050HCID 122392050, compound

Reagents, catalysts & solvents 5

HCID 10796Cesium carbonateReagentHCID 167845palladium(II) acetateCatalystHCID 4643319tert-ButyldicyclohexylphosphineCatalystHCID 7854PropionitrileSolventHCID 117669-PhenylanthraceneInternal standard

Conditions

Temperature
100 °C

Sources & evidence

ORD record
ord-e7f1714e410d441c8865f4059a76f9f4
Source dataset
39k HTE dataset from Pfizer
Original link
View source

Linked notes

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