(R)-(+)-1-Boc-3-aminopyrrolidine → HCID 178452029, compound
Reaction equation
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:13][C@H:11]([NH2:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3].Br[c:14]1[n:22][c:21]([c:17]2[cH:16][cH:15]1)[cH:20]c[cH:19][c:18]2[C:23]#[N:24]>>[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:13][C@H:11]([NH:12][c:17]2[cH:23][n:24][c:14]([N:22]3[CH2:19][CH2:18]O[CH2:20][CH2:21]3)[cH:15][cH:16]2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3]Participants
7
Conditions
- Temperature
- 120 °C
Sources & evidence
- ORD record
- ord-2e5e70c64b5d47c5960902614c01eb01
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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