(R)-(+)-1-Boc-3-aminopyrrolidine → HCID 178452029, compound
Reaction equation
[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:13][C@H:11]([NH2:12])[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3].Br[c:14]1[cH:19][n:18][c:17]([N:20]2[CH2:25][CH2:24][O:23][CH2:22][CH2:21]2)[cH:16][cH:15]1>>[CH3:1][C:2]([O:5][C:6]([N:8]1[CH2:13][C@H:11]([NH:12][c:14]2[cH:19][n:18][c:17]([N:20]3[CH2:25][CH2:24][O:23][CH2:22][CH2:21]3)[cH:16][cH:15]2)[CH2:10][CH2:9]1)=[O:7])([CH3:4])[CH3:3]Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 110 °C
Sources & evidence
- ORD record
- ord-9902b518753f40d5851298765cd7e89a
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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