Ethyl Acetate → Tert-butyl 4-(4-amino-3-fluorophenyl)piperazine-1-carboxylate
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16]([F:23])[c:17]([N+:20]([O-:21])=[O:22])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31].[H:24][H:25]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][N:11]([c:14]2[cH:15][c:16]([F:23])[c:17]([NH2:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1Participants
4
Sources & evidence
- ORD record
- ord-c8158f12c43d4924b6657f82237e60dc
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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