Bicarbonate Ion → benzyl 2-[[3-(1H-indol-6-yl)phenyl]carbamoyl]pyrrolidine-1-carboxylate

HRID 202088

Reaction equation

HRID 202088 reaction equation
[Br:34][c:35]1[cH:36][cH:37][c:38]2[cH:39][cH:40][nH:41][c:42]2[cH:43]1.[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([C:16]([NH:17][c:18]2[cH:19][c:20]([B:24]3[O:25][C:26]([CH3:27])([CH3:28])[C:29]([CH3:30])([CH3:31])[O:32]3)[cH:21][cH:22][cH:23]2)=[O:33])[CH2:13][CH2:14][CH2:15]1.[CH3:54][OH:55].[Na+:48].[O-:44][C:45]([OH:46])=[O:47].[O:49]=[CH:50][N:51]([CH3:52])[CH3:53]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[N:11]1[CH:12]([C:16]([NH:17][c:18]2[cH:19][c:20](-[c:35]3[cH:36][cH:37][c:38]4[cH:39][cH:40][nH:41][c:42]4[cH:43]3)[cH:21][cH:22][cH:23]2)=[O:33])[CH2:13][CH2:14][CH2:15]1

Participants

7

Reactant 6

HCID 769Bicarbonate IonHCID 887MethanolHCID 923Sodium ionHCID 6228DimethylformamideHCID 6764936-BromoindoleHCID 69023528Benzyl 2-[[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]carbamoyl]pyrrolidine-1-carboxylate

Product 1

HCID 69023538benzyl 2-[[3-(1H-indol-6-yl)phenyl]carbamoyl]pyrrolidine-1-carboxylate

Sources & evidence

ORD record
ord-1453e15d39b446b2b4405b156257d84e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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