Ethylene → 5,8-dichloro-3,4-dihydroisoquinolin-1(2H)-one
Reaction equation
[CH2:1]=[CH2:2].CO[NH:3][C:4]([c:6]1[c:12]([Cl:13])[cH:11][cH:10][c:8]([Cl:9])[cH:7]1)=[O:5]>>[Cl:9][c:8]1[c:7]([c:6]2[c:12]([Cl:13])[cH:11][cH:10]1)[CH2:2][CH2:1][NH:3][C:4]2=[O:5]Participants
7
Reactant 2
Product 1
Reagents, catalysts & solvents 4
Conditions
- Temperature
- 25 °C
Sources & evidence
- ORD record
- ord-3106604bfb6045e6891bbdaefe1a3689
- Source dataset
- 39k HTE dataset from Pfizer
- Original link
- View source
Reaction notes
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