Potassium Carbonate → HCID 68554356, compound
Reaction equation
Cl[C:2]1[N:3]=[N:4][C:5]([C:8]2[O:12][N:11]=[C:10]([CH3:13])[N:9]=2)=[CH:6][CH:7]=1.[F:14][C:15]1[CH:16]=[C:17]([N:21]2[CH2:25][C:24]3([CH2:30][CH2:29][NH:28][CH2:27][CH2:26]3)[O:23][C:22]2=[O:31])[CH:18]=[CH:19][CH:20]=1.C(=O)([O-])[O-].[K+].[K+]>>[F:14][C:15]1[CH:16]=[C:17]([N:21]2[CH2:25][C:24]3([CH2:26][CH2:27][N:28]([C:2]4[N:3]=[N:4][C:5]([C:8]5[O:12][N:11]=[C:10]([CH3:13])[N:9]=5)=[CH:6][CH:7]=4)[CH2:29][CH2:30]3)[O:23][C:22]2=[O:31])[CH:18]=[CH:19][CH:20]=1Participants
4
Procedure
The object product (82 mg, 57%) was obtained in the same manner as in Example 1 and using 3-chloro-6-(3-methyl-1,2,4-oxadiazol-5-yl)pyridazine (70 mg) obtained in Example 43(2), 3-(3-fluorophenyl)-1-oxa-3,8-diazaspiro[4.5]decan-2-one (80 mg) obtained in Example 29(3) and potassium carbonate (50 mg).