Bromide ion → 5-Hydroxy-5-propyl-2-(4-trifluoromethoxy-phenyl)-hexahydro-cyclopenta[c]pyrrol-1-one
Reaction equation
[Br-:1].[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH2:2]([CH2:3][CH3:4])[Mg+:5].[F:6][C:7]([O:8][c:9]1[cH:10][cH:11][c:12]([N:15]2[C:16](=[O:24])[CH:17]3[CH:18]([CH2:19]2)[CH2:20][C:21](=[O:23])[CH2:22]3)[cH:13][cH:14]1)([F:25])[F:26].[OH2:27]>>[CH2:2]([CH2:3][CH3:4])[C:21]1([OH:23])[CH2:20][CH:18]2[CH:17]([C:16](=[O:24])[N:15]([c:12]3[cH:11][cH:10][c:9]([O:8][C:7]([F:6])([F:25])[F:26])[cH:14][cH:13]3)[CH2:19]2)[CH2:22]1Participants
6
Sources & evidence
- ORD record
- ord-bec1d05bcfe5405a9ada2d35fcd145eb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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