Tetrahydrofuran → 6-Cyclopropylmethoxy-5-(1-hydroxy-cyclobutyl)-pyridine-2-carboxylic acid
Reaction equation
[Br:6][c:7]1[cH:8][cH:9][c:10]([C:18](=[O:19])[OH:20])[n:11][c:12]1[O:13][CH2:14][CH:15]1[CH2:16][CH2:17]1.[C:21]1(=[O:25])[CH2:22][CH2:23][CH2:24]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5]>>[c:7]1([C:21]2([OH:25])[CH2:22][CH2:23][CH2:24]2)[cH:8][cH:9][c:10]([C:18](=[O:19])[OH:20])[n:11][c:12]1[O:13][CH2:14][CH:15]1[CH2:16][CH2:17]1Participants
5
Sources & evidence
- ORD record
- ord-6860e9691187416b9a9fdfced1839d35
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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