Benzaldehyde → Benzaldehyde-4-chlorophenylnitrone

HRID 2049437Notes

Reaction equation

HRID 2049437 reaction equation
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([NH:8][OH:9])=[CH:4][CH:3]=1.[CH:10](=O)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.C1(C(C2C=CC=CC=2)=[N+](Cl)[O-])C=CC=CC=1>C(O)C>[C:11]1([CH:10]=[N+:8]([C:5]2[CH:6]=[CH:7][C:2]([Cl:1])=[CH:3][CH:4]=2)[O-:9])[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

5

Reactant 3

HCID 240BenzaldehydeHCID 699834-ChlorophenylhydroxylamineHCID 178526349HCID 178526349, compound

Product 1

HCID 275545Benzaldehyde-4-chlorophenylnitrone

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

p-Chlorophenylhydroxylamine (0.05 moles) was dissolved in warm 95% ethanol (20 cc) and was treated with benzaldehyde (0.05 moles) with vigorous stirring. The solid which formed was collected, washed with 95% ethanol, and recrystallized from ethanol to give 512 g. of α-phenyl-N-chlorophenylnitrone (m.p. 179°-82°).

Workup

  1. customThe solid which formed
  2. customwas collected
  3. washwashed with 95% ethanol
  4. customrecrystallized from ethanol
  5. customto give 512 g

Sources & evidence

ORD record
ord-f7ab9b2b911f437d895c72f75825324f
Source dataset
uspto-grants-1980_04
Patent number
US04197314

Reaction notes

Loading…