1-Iodopropane → HCID 20330058, compound

Reaction equation

[C:1]([C:4]1[C:5]([N:16]=[CH:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[NH:7][C:8]=1[CH3:9])(=[O:3])[CH3:2].[CH2:24](I)[CH2:25][CH3:26]>>[C:1]([C:4]1[C:5]([N:16]=[CH:17][C:18]2[CH:23]=[CH:22][CH:21]=[CH:20][CH:19]=2)=[C:6]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)[N:7]([CH2:24][CH2:25][CH3:26])[C:8]=1[CH3:9])(=[O:3])[CH3:2]

Participants

Reactant 2

HCID 336431-Iodopropane

HCID 12789002HCID 12789002, compound

Product 1

HCID 20330058HCID 20330058, compound

Procedure

Starting from the compound of Example 46 and propyl iodide, and using procedure (a) of Example 49, 4-acetyl-3-benzylideneamino-5-methyl-2-phenyl-1-propyl-pyrrole is obtained as an oily substance. This compound is hydrolyzed as in prodedure (b) of Example 40. Yield of the title compound: 50%, m.p. 113-15° C. (from ethanol).

Sources & evidence

ORD record: ord-c8e175baa6674bbd95ceb0b7aaae9488
Source dataset: uspto-grants-1980_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04198502

Reaction notes

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