Diisopropylethylamine → 2-[(4-{2-[(5-Ethylpyrimidin-2-yl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester

HRID 205609

Reaction equation

HRID 205609 reaction equation
[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15]([C:16]([CH3:17])([CH3:18])[S:19][c:20]1[s:21][cH:22][c:23]([CH2:25][CH2:26][NH2:27])[n:24]1)=[O:28].[CH:1]([N:2]([CH2:3][CH3:4])[CH:5]([CH3:6])[CH3:7])([CH3:8])[CH3:9].[Cl:29][c:30]1[n:31][cH:32][c:33]([CH2:36][CH3:37])[cH:34][n:35]1>>[C:10]([CH3:11])([CH3:12])([CH3:13])[O:14][C:15]([C:16]([CH3:17])([CH3:18])[S:19][c:20]1[s:21][cH:22][c:23]([CH2:25][CH2:26][NH:27][c:30]2[n:31][cH:32][c:33]([CH2:36][CH3:37])[cH:34][n:35]2)[n:24]1)=[O:28]

Participants

4

Reactant 3

HCID 81531DiisopropylethylamineHCID 35727632-Chloro-5-ethylpyrimidineHCID 597594492-{[4-(2-Aminoethyl)-1,3-thiazol-2-yl]thio}-2-methylpropionic acid tert-butyl ester

Product 1

HCID 597588712-[(4-{2-[(5-Ethylpyrimidin-2-yl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester

Sources & evidence

ORD record
ord-52226781e17148abb622f0affeb0dbca
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

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