Bicarbonate Ion → N-[6-(3-{[isopropylcarbamoyl]amino}phenoxy)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide

HRID 205626

Reaction equation

HRID 205626 reaction equation
[C:36](=[O:37])([O-:38])[OH:39].[N:24](=[C:25]=[O:26])[CH:27]([CH3:28])[CH3:29].[NH2:1][c:2]1[cH:3][c:4]([O:5][c:6]2[cH:7][cH:8][c:9]3[n:10]([cH:11]2)[cH:12][c:13]([NH:15][C:16](=[O:17])[CH:18]2[CH2:19][CH2:20]2)[n:14]3)[cH:21][cH:22][cH:23]1.[Na+:40].[cH:30]1[cH:31][cH:32][n:33][cH:34][cH:35]1>>[NH:1]([c:2]1[cH:3][c:4]([O:5][c:6]2[cH:7][cH:8][c:9]3[n:10]([cH:11]2)[cH:12][c:13]([NH:15][C:16](=[O:17])[CH:18]2[CH2:19][CH2:20]2)[n:14]3)[cH:21][cH:22][cH:23]1)[C:25]([NH:24][CH:27]([CH3:28])[CH3:29])=[O:26]

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 1049PyridineHCID 61277Isopropyl isocyanateHCID 57749361N-[6-(3-aminophenoxy)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide

Product 1

HCID 57749359N-[6-(3-{[isopropylcarbamoyl]amino}phenoxy)imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide

Sources & evidence

ORD record
ord-04df20076d4b4f8e9581c38858227557
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Linked notes

Loading…