Dichloromethane → (r/s)-3-(Tert-butoxycarbonylamino)-1-(4-bromo-5-isoquinolinesulfonyl)pyrrolidine

Reaction equation

[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([S:12](=[O:13])(=[O:14])[Cl:15])[c:11]12.[C:16]([CH3:17])([CH3:18])([CH3:19])[O:20][C:21](=[O:22])[NH:23][CH:24]1[CH2:25][NH:26][CH2:27][CH2:28]1.[CH2:36]([Cl:37])[Cl:38].[CH3:29][CH2:30][N:31]([CH2:32][CH3:33])[CH2:34][CH3:35]>>[Br:1][c:2]1[cH:3][n:4][cH:5][c:6]2[cH:7][cH:8][cH:9][c:10]([S:12](=[O:13])(=[O:14])[N:26]3[CH2:25][CH:24]([NH:23][C:21]([O:20][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:22])[CH2:28][CH2:27]3)[c:11]12