Phenylacetic Acid → 2-Benzyl-5-phenyl-oxazole-4-carboxylic acid

HRID 2065096

Reaction equation

HRID 2065096 reaction equation
[CH:1]1[CH:6]=[CH:5][C:4]([CH:7]([OH:13])[CH:8]([NH2:12])[C:9]([OH:11])=[O:10])=[CH:3][CH:2]=1.[C:14]1([CH2:20][C:21](O)=O)[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1>>[CH2:20]([C:21]1[O:13][C:7]([C:4]2[CH:3]=[CH:2][CH:1]=[CH:6][CH:5]=2)=[C:8]([C:9]([OH:11])=[O:10])[N:12]=1)[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=1

Participants

3

Reactant 2

HCID 999Phenylacetic AcidHCID 94134DL-Phenylserine

Product 1

HCID 669284992-Benzyl-5-phenyl-oxazole-4-carboxylic acid

Procedure

Prepared starting from DL-3-phenylserine hydrate following sequentially general procedures Y, Z with phenyl-acetic acid, Z1 and Z2. LC-MS-conditions 02: tR=0.95 min; [M+H]+=220.18.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-b9ad3b865f4f424c9bf586c5b8a8d8ba
Source dataset
uspto-grants-2012_10
Patent number
US08288419B2

Linked notes

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